Rare Association of a Calcifying Odontogenic Cyst and an Odontoma: A Case Report and Diagnostic Discussion

Abstract

The calcifying odontogenic cyst (Gorlin cyst) is a rare benign odontogenic lesion that may be associated with other developmental anomalies, particularly an odontoma. [4]
We report the case of an 18-year-old patient presenting with a progressive, hard, non-inflammatory, and painless swelling of the right maxilla, associated with palatal bulging and cortical expansion. [1] Computed tomography revealed two well-defined radiopaque lesions closely related to the dental structures and associated with impacted permanent teeth. The main differential diagnoses included cementoblastoma, odontoma, and calcifying odontogenic cyst. Histopathological examination of the biopsy specimen established the diagnosis of a calcifying odontogenic cyst associated with an odontoma, characterized by an odontogenic epithelial lining exhibiting ameloblastic differentiation, ghost cells, dentinoid material, and rudimentary dental structures.
This case highlights the challenges of preoperative diagnosis of calcified odontogenic lesions and emphasizes the importance of clinicoradiological and histopathological correlation.